NETGE-PLUS is optimized to be used on a Google Chrome browser


Welcome to NETGE-PLUS

NETGE-PLUS is a web-server for standard and network-based functional interpretation of gene sets of human and model organisms, including S. scrofa, S. cerevisiae, E. coli and A. thaliana.
NETGE-PLUS enables the functional enrichment of both simple and ranked lists of protein/genes, also introducing the possibility of exploring relationships among KEGG pathways.


5 organisms | 6 annotation resources | 68,407 functional sets
NETGE-PLUS has completed 1327 analyses.

Submit a gene set

To start using NETGE-PLUS you simply need to paste a gene/protein set [one column for ORA (only IDs) or two columns for GSEA (IDs plus numeric values) in the text area below.
Then, select the desired parameters and submit the job.


Example - ORA - Non-alcoholic Fatty Liver Disease (NAFLD)
Example - GSEA - Effect of the Pseudorabies Virus infection on the swine transcriptome

(The SYSTEMATIC_GENE_NAME has been introduced for E. coli, S. cerevisiae and A. thaliana; see help for details)
(Mandatory)
(Reactome is not available for E. coli)
(ORA: Over Representation Analysis, GSEA: Gene Set Enrichment Analysis)
(Bonferroni is available only for ORA)
(Optional)

To cite your use of the NETGE-PLUS, please reference:
Bovo S, Martelli PL, Di Lena P, Casadio R. NETGE-PLUS: standard and network-based gene enrichment analysis in human and model organisms.
J Proteome Res. 2020 Jan 23. doi: 10.1021/acs.jproteome.9b00749. PubMed PMID: 31971806